General Hospital spoilers hint Sam McCall (Kelly Monaco) may not have died from an accidental error on the surgical team’s behalf. Instead, she could have been murdered.

The fans are already chattering about who may have had motive to kill a saint like Sam. She was going under the knife to save Lulu Falconeri’s (Alexa Havins) life. Who on Earth would think she deserved to die?

Sam had very few enemies, but it’s possible that she could have been collateral damage in someone else’s war. She was close to many people who were on the wrong side of the law. Is that what happened here?

General Hospital Spoilers — Jason Morgan’s Enemies Could Have Come Knocking

No one seems to suspect right now that anyone Jason Morgan (Steve Burton) was attached to could have come back to haunt him. Would they have any idea that his ex-wife of several years now being taken would hit him this hard?

Maybe, maybe not. But it’s safe to say he never wanted the mother of his child to die. Is Sam’s death a murder as an act of revenge from a former mob enemy gone rogue?

GH Spoilers Claim Dante’s Line of Work Isn’t Perfectly Safe

Of course, just because Dante Falconeri (Dominic Zamprogna) was working on the right side of the law doesn’t mean he doesn’t have a pile of enemies just the same as Jason does.

Furthermore, his would probably be more current — since Jason was missing for two years prior to coming back from the grae earlier this year.

Likewise, it would make more sense that someone would think they could hurt Dante by killing the woman he loves than someone wanting to hurt Jason by killing a woman he used to love.

General Hospital Spoilers — Cyrus Renault, Isaiah, And Steven Webber?

Some fans have speculated that Cyrus Renault (Jeff Kober) may have been behind Sam’s death. He’s been lurking around Lulu for months — and without Laura Collins’ (Genie Francis) expressed permission. Maybe he thought this was some way to stick it to Julian Jerome (William deVry).

It could also be that we don’t know nearly enough about Dr. Isaiah Gannon (Sawandi Wilson) to assume he didn’t play a role here. His past sounds murky, at best.